A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia
Summary: A major hurdle in the treatment of cancer is chemoresistance induced under hypoxia that is characteristic of tumor microenvironment.Triptolide, a potent inhibitor of eukaryotic Freezer Door Handle Base transcription, possesses potent antitumor activity.However, its clinical potential has been limited by toxicity and water solubility.To add